Prediction of Protein Retention in Ion-Exchange Systems

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Table of Contents

Prediction of Protein Retention in Ion-Exchange Systems

Abstract

Motivation

Chromatographic Procedure

Criteria for Probe Proteins

Probe Proteins

Representative Proteins

Quantitative Structure Efficacy Relationship Descriptors

Transferable Atom Equivalent Descriptors

Partial Least Squares approach

Modeling Details

QSER Model for Protein Retention and Prediction Results

Possible Points of Improvement for this Model

Conclusions

Acknowledgements

Author: N. Sukumar

Email: nagams@rpi.edu

Home Page: http://www.chem.rpi.edu/chemweb/recondoc/

 

 

 

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